Applied Research Projects and Consulting
I
am offering Consulting Services in Flow Cytometry and Cell-Based
Assay Design.
Contact jpetrizigtp.cat
for more information.
Research Projects (1991-2022). More than thirty years of experience
in Flow Cytometry analysis of Cancer, Multidrug Resistance and Stem
Cells.
Immune
response. PD-1/PD-L1 checkpoint.
Nanocytometry. Flow virometry. Nanoplastics.
Platelet Function Analysis. Platelet Function Analysis.
Design of consensus protocols for safety, quality and
standardization of CD34+ cells after-thawing.
Study of the mechanisms by which ABC transporters differentially
activates low- or high-level transduction
cell signaling: Potential role to protect the stem cell
compartment.
The use of anticancer drug libraries to study the reversal of
multidrug resistance in Side Population cancer stem cells.
Sequential Immune Disruptions in Chronic Fatigue Syndrome.
Murine
xenograft models for human ovary, testis, prostate, pancreas and
colon cancers: Detection of bone marrow infiltration by Side
Population cells.
Development of a new Cytomic Platform for stem cell systems
biology.
FACS-based isolation of normal and cancer stem cells originated
from the Side Population. Association with the gene expression in
highly purified preparations of stem cell subsets.
Flow-FISH and CD34+/CD34- cell analysis as a measure of the
presence and quality of Hematopoietic Stem Cells.
Quality Assessment of Autologous Haematopoietic Blood Progenitor
and Stem Cell Grafting: A prospective registration study.
Identification and characterization of prostate cancer stem cells.
Hormone-resistance and intermittent androgen supression.
Study of the contribution of vascular progenitor cells in vascular
lesion and in repair mechanisms in pulmonary circulation in
COPD.
New flow cytometric strategies for whole blood
immunostaining.
Gene expression alterations, apoptosis and mitochondrial toxicity
in adipocytes. Lipodistrophy ethiopathogenesis and its association
with antiretroviral therapy.
Preparation and characterization of anti-CD34 immunoliposomes
entrapping doxorubicin. Gene transfer.
Positive selection of CD34+ cells using immunoliposomes. Potential
applications for autologous bone marrow transplantation.
Characterization and selection of normal and malignant progenitors
in chronic myelogenous leukemia.
Study of regulatory factors affecting growth, cell proliferation
and prognosis in hypophysary adenomas.
Genetic instability in colorectal cancers and its role in tumor
progression. Molecular prognostic factors.
Detection and significance of minimal residual disease in acute
myelogenous leukemia and non-Hodgkin lymphomas.
Prognostic value of DNA ploidy in women with node negative breast
cancer.